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Our lab is dedicated to understanding breast and ovarian cancer with the goal of deciphering the molecular mechanisms of chemotherapy resistance and cell death signaling.
We aim to identify novel mechanisms of cell death-resistance in breast and ovarian cancer (mitochondrial and non-mitochondrial) and discover small molecules to intervene these pathways to increase the efficiency of cancer therapeutics in patients. Our ultimate goal of research is to deepen the knowledge about breast and ovarian cancer pathogenesis, to identify possible causes of drug-resistance in cancer patients and to apply what we learn to improve therapy of human cancers in collaborative initiatives with clinicians and oncologists. |
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